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AI4Pandemics Talk #12: Pranesh Padmanabhan, The University of Queensland
December 15, 2021 @ 10:00 am - 10:45 am
Title: Predicting the effectiveness of COVID-19 vaccines and treatments
Abstract:
The raging global COVID-19 pandemic has triggered enormous global efforts to develop and improve COVID-19 vaccines and antiviral treatments. Predicting the efficacy of COVID-19 vaccines and treatments would aid in the identification of optimal vaccine/treatment development and usage strategies. In this talk, I will first describe our multiscale mathematical model that presents mechanistic links between COVID-19 vaccine efficacies and the vaccine-induced neutralisation antibody responses. I will then discuss a mathematical model of SARS-CoV-2 entry into target cells that unravels an unexpected synergy between antivirals targeting the different virus entry pathways.